NORMAN, Okla. — Kyle Kempt passed for 343 yards and three touchdowns, including a 25-yarder to Allen Lazard that put Iowa State ahead with 2:19 left and Joel Lanning made plays on offense and defense to lead the Cyclones to a stunning 38-31 victory over No. 3 Oklahoma on Saturday.
The loss snapped Oklahoma’s nation-leading 14-game winning streak and the Sooners’ 18-game run against the Cyclones that dated to 1990. It was just Iowa State’s second victory over Oklahoma since 1961, and the Cyclones (3-2, 1-1 Big 12) did it without their starting quarterback.
MICHIGAN STATE 14, NO. 7 MICHIGAN 10
ANN ARBOR, Mich. — Brian Lewerke ran for a touchdown and threw for a score in the first half and Michigan State held on to beat Michigan.
The Wolverines had the ball with a chance to drive for a go-ahead TD, but a heave from the Spartans 37 as time expired hit the turf near the goal line.
NO. 1 ALABAMA 27, TEXAS A&M 19
COLLEGE STATION, Texas — Damien Harris ran for 124 yards and a touchdown, and Jalen Hurts had a touchdown pass and ran for another score to help Alabama remain undefeated.
The Aggies (4-2, 2-1 Southeastern Conference), who entered the game as 26 1/2 point underdogs, made the game interesting, but in the end freshman quarterback Kellen Mond was simply too inexperienced to help them topple a team as talented as Alabama.
NO. 2 CLEMSON 28, WAKE FOREST 14
CLEMSON, S.C. — Kelly Bryant threw for 200 yards and a touchdown before leaving with an ankle injury and Clemson beat Wake Forest to reach to 6-0 for a third straight season.
NO. 4 PENN STATE 31, NORTHWESTERN 7
EVANSTON, Ill. — Trace McSorley threw for 245 yards and a touchdown, Saquon Barkley ran for two scores in the second half for Penn State.
McSorley completed 25 of 34 passes. He threw a 10-yard touchdown pass to backup quarterback Tommy Stevens in the second quarter and added a 5-yard scoring run in the fourth.
NO. 5 GEORGIA 45, VANDERBILT 14
NASHVILLE, Tenn. — Nick Chubb ran for two touchdowns and 138 yards, and Georgia routed Vanderbilt despite missing three players from the Bulldogs’ stingy defense.
NO. 8 TCU 31, NO. 23 WEST VIRGINIA 24
FORT WORTH, Texas — Kenny Hill avoided a defender in the backfield and lunged forward through two more for a 3-yard touchdown run with 2:53 left and TCU remained the Big 12’s only undefeated team.
NO. 10 OHIO STATE 62, MARYLAND 14
COLUMBUS, Ohio — J.T. Barrett threw for three touchdowns and ran for another in the first half, and Ohio State had its most dominant defensive effort in nearly 60 years.
NO. 12 AUBURN 44, MISSISSIPPI 23
AUBURN, Ala. — Kerryon Johnson rushed for a career-high 204 yards and three touchdowns for Auburn.
NO. 13 MIAMI 24, FLORIDA STATE 20
TALLAHASSEE, Fla. — Malik Rosier threw a 23-yard touchdown pass to Darrell Langham with 6 seconds remaining and Miami beat Florida State to end a seven-game losing streak in the series.
NO. 14 SOUTHERN CAL 38, OREGON STATE 10
LOS ANGELES — Sam Darnold threw for 316 yards and three touchdowns, Ronald Jones II ran for a touchdown and Southern California beat Oregon State.
NO. 16 VIRGINIA TECH 23, BOSTON COLLEGE 10
BOSTON — Josh Jackson threw for 322 yards and a touchdown and Virginia Tech bounced back from a loss to defending national champion Clemson.
LSU 17, NO. 21 FLORIDA 16
GAINESVILLE, Fla. — Danny Etling threw a short touchdown pass in the second half and LSU rebounded from a stunning home loss to beat Florida.
NO. 21 NOTRE DAME 33, NORTH CAROLINA 10
CHAPEL HILL, N.C. — Josh Adams ran for 118 yards, including a 73-yard touchdown dash for Notre Dame.
Deon McIntosh added 124 yards rushing and two scores for the Fighting Irish (5-1). They played without starting quarterback Brandon Wimbush due to a right foot injury.
Wimbush was on the sideline as the No. 2 QB behind Ian Book, though the Fighting Irish had no trouble surpassing the win total from a frustrating 2016 season.
Book threw for a score and had two interceptions. Notre Dame had 487 yards, 341 coming on the ground.
Chazz Surratt threw a 25-yard touchdown pass to Anthony Ratliff-Williams before halftime in the only noteworthy offensive play for the Tar Heels (1-5).